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EBP Compendium: Summary of Clinical Practice Guideline

American Academy of Neurology
Practice Parameter: Management of Dementia (An Evidence-Based Review)

Doody, R. S., Stevens, J. C., et al. (2001).
Neurology, 56(9), 1154-66.

AGREE Rating: Highly Recommended


This guideline provides recommendations for pharmacologic management of individuals with dementia and the educational and non-pharmacological management of individuals with dementia and their caregivers. The target audience of this guideline are health care professionals, including neurologists, physicians, and other clinicians. Levels of evidence are provided and defined as follows: A standard is a “principle for patient management that reflects a high degree of clinical certainty” (p. 1156) and is usually based on evidence from well-designed, individual randomized controlled trials (RCT) or meta-analyses containing RCTs. A guideline for patient management reflects moderate clinical certainty and is usually based on well-designed, observational studies with concurrent controls. A practice option is a “strategy for patient management for which the clinical utility is uncertain” (p. 1156) due to inconclusive or conflicting evidence or opinion.


  • Treatment
    • Cognitive-Communication
      • Compensatory Treatments
        • General Findings - Recommendations for nonpharmacologic interventions (other than education) may include graded assistance, practice, and positive reinforcement to increase functional independence (Guideline).
      • Restorative Treatments
        • General Findings - While evidence is only suggestive, some individuals with dementia may benefit from cognitive remediation and commands provided at the appropriate comprehension level (Practice Option).
        • Simulated Presence Therapy - There is suggestive evidence that some individuals with dementia may benefit from simulated presence therapy (Practice Option).

Keywords: Dementia; Cognition

Access the Guideline

Added to Compendium: November 2010

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