EBP Compendium: Summary of Systematic Review
National Institutes of Health
Is Hearing Loss Due to Mutations in the Connexin 26 Gene Progressive?
Gopalarao, D., Kimberling, W. J., et al.
International Journal of Audiology, 47(1), 11-20.
Indicators of Review Quality:
The review addresses a clearly focused question
Criteria for inclusion of studies are provided
Search strategy is described in sufficient detail for replication
Included studies are assessed for study quality
Quality assessments are reproducible
Description: This is a meta-analysis of studies investigating mutations in the connexin 26 gene as a cause of progressive hearing loss in individuals.
Question not specifically stated.
Population: Not further specified
Intervention/Assessment: Not applicable
Number of Studies Included: 8
Years Included: Not stated.
"[Persons with this genetic mutation] who have residual hearing should be monitored with repeat audiological evaluations in the same meticulous manner as other patients with sensorineural hearing loss" (p. 19).
Keywords: Congenital Disorders, Hearing Loss
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Added to Compendium: January 2012